Safety & Efficacy

Demonstrated Effectiveness

The Blood Pressure Lowering Effect of the Combination of Amlodipine and Celecoxib is Similar to that Seen with Amlodipine Alone.


The Blood Pressure Lowering Effect of the Combination of Amlodipine and Celecoxib is Similar to that Seen with Amlodipine Alone.

1 Study to Evaluate the Effect of Celecoxib on the Efficacy and Safety of Amlodipine in Subjects with Hypertension Requiring Antihypertensive Therapy (NCT02172040) Available from: http://www.Clinicaltrials.gov/ct2/show/NCT02172040
* Error bars – standard error of mean

Study results demonstrated that the combination of celecoxib and amlodipine provided similar blood pressure reduction to an equal dose of amlodipine.

There are no studies of the combination of celecoxib and amlodipine demonstrating reductions in the signs and symptoms of osteoarthritis, but one of the components, celecoxib, has demonstrated such effects. There are also no long-term studies to evaluate cardiovascular safety for the combination of celecoxib and amlodipine.